Type I vaccine-derived polioviruses in China from 1995 to 2019
نویسندگان
چکیده
منابع مشابه
Neurovirulent Vaccine-Derived Polioviruses in Sewage from Highly Immune Populations
BACKGROUND Vaccine-derived polioviruses (VDPVs) have caused poliomyelitis outbreaks in communities with sub-optimal vaccination. Israeli environmental surveillance of sewage from populations with high (>95%) documented vaccine coverage of confirmed efficacy identified two separate evolutionary clusters of VDPVs: Group 1 (1998-2005, one system, population 1.6x10(6)) and Group 2 (2006, 2 systems,...
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Widespread use of oral poliovirus vaccine has led to an ≈99.9% decrease in global incidence of poliomyelitis (from ≈350,000 cases in 1988 to 74 cases in 2015) and eradication of wild-type poliovirus serotypes 2 and 3. However, patients with primary immunodeficiency might shed vaccine-derived polioviruses (VDPVs) for an extended period, which could pose a major threat to polio eradication progra...
متن کاملAre Circulating Type 2 Vaccine-derived Polioviruses (VDPVs) Genetically Distinguishable from Immunodeficiency-associated VDPVs?
Public health response to vaccine-derived poliovirus (VDPV) that is transmitted from person to person (circulating VDPV [cVDPV]) differs significantly from response to virus that replicates in individuals with primary immunodeficiency (immunodeficiency-associated VDPV [iVDPV]). cVDPV outbreaks require a community immunization response, whereas iVDPV chronic infections require careful patient mo...
متن کاملGaps in our knowledge about transmission of vaccine-derived polioviruses.
It has long been known that oral poliovirus vaccine (OPV) viruses are transmissible ¿to some degree¿ between vaccinated individuals and their contacts. This property has generally been considered an advantage of these vaccines, since it can spread immunity, despite the fact that the viruses sometimes revert to virulence and hence can also cause vaccine-attributable paralytic poliomyelitis in v...
متن کاملDetection of vaccine-derived polioviruses in Mexico using environmental surveillance.
BACKGROUND Early detection and control of vaccine-derived poliovirus (VDPV) emergences are essential to secure the gains of polio eradication. METHODS Serial sewage samples were collected in 4 towns of Mexico before, throughout, and after the May 2010 oral poliovirus vaccine (OPV) mass immunization campaign. Isolation and molecular analysis of polioviruses from sewage specimens monitored the ...
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ژورنال
عنوان ژورنال: Biosafety and Health
سال: 2019
ISSN: 2590-0536
DOI: 10.1016/j.bsheal.2019.12.002